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The Global Fund to Fight AIDS, Tuberculosis and Malaria: A smart, lifesaving U.S. investment

decline in combined death rate from AIDS, TB and malaria



Is the world’s largest global health funder

Invests more than $5 billion a year in programs run by local experts and governments

Builds stronger health systems, health security and pandemic preparedness

Accelerates the end of the world’s deadliest infectious diseases


Ending AIDS

Translating Progress into Success to End the AIDS Epidemic is a collaboration between amfAR, AVAC, and Friends of the Global Fight, with technical assistance from the Henry J. Kaiser Family Foundation. The report was conceptualized to take stock of how far we have come – and how far we have to go – toward ending HIV and AIDS around the world.

Ending TB

TB is curable. We need renewed and sustained political will to combat this epidemic. We know we can end the TB epidemic. It is a matter of scaling up effective programs, dedicating sufficient resources and mobilizing the political will. This report highlights six locations where communities made impressive progress to significantly reduce TB cases and deaths – from California in the United States to Tomsk, Russia and Karachi, Pakistan.

Ending Malaria

In the last two decades, global efforts against malaria have reached a tipping point, allowing health leaders for the first time to move beyond merely controlling this ancient disease and instead commit to ending it.


“We are talking about people’s lives”: Fighting TB at the Global Fund

During the 1990s, when Dr. Eliud Wandwalo was working as a clinician in a hospital in western Tanzania, he watched as tuberculosis (TB) tore through a ward of patients who could scarcely bear the burden of another life-threatening disease. “The majority of people who had HIV were dying of TB,” said Wandwalo, who is now…

What Does $1.65 Billion Buy?

Providing a $1.65 billion appropriation for the Global Fund in fiscal year 2025 would support lifesaving interventions and help continue progress toward ending the epidemics of AIDS, tuberculosis and malaria. Click on the infographic below to learn about the far-reaching impact of U.S. investment.