Global Fund Releases Investment Case for Seventh Replenishment

Increased investments to end the AIDS, TB and malaria epidemics will save 20 million lives

Washington, D.C. – The Global Fund released its investment case today, projecting that at least $18 billion is needed in new investments to get back on track to end the epidemics of AIDS, tuberculosis and malaria by 2030. This new funding will save an additional 20 million lives.

“For two decades, generous U.S. support of the Global Fund has mobilized global investment and achieved dramatic progress against infectious disease,” said Chris Collins, president and CEO of Friends of the Global Fight. “The COVID-19 pandemic has been a major setback in the fight against AIDS, TB, and malaria, yet these programs innovated and helped countries respond to the new pandemic.”

“With the new investment case released today, the Global Fund has provided a roadmap for accelerated progress against AIDS, TB and malaria and stronger pandemic preparedness for the world,” Collins said. “U.S. leadership will be needed again to realize the exciting potential outlined in today’s report. We welcome Secretary of State Antony Blinken’s call to make the seventh replenishment ‘the most successful replenishment to date.’ The Global Fund should be at the center as the global community develops new approaches to strengthened pandemic preparedness.”

Based on the new investment case, Friends of the Global Fight urges Congress to appropriate at least $2 billion to the Global Fund in fiscal year 2023 and for the Biden Administration to pledge at least $6 billion to the Global Fund over the full fiscal year 2023-2025 replenishment cycle. These figures are consistent with the U.S. traditionally providing one-third of total Global Fund resources, spurring other donors to invest.

Just yesterday, 137 members of Congress, led by Reps. Barbara Lee (D-CA) and Michael McCaul (R-TX) wrote to President Biden, urging him to meet the moment with a bold and increased pledge for this upcoming replenishment.

“We’ve seen how remarkably effective and agile the Global Fund is,” said Dr. Jeffrey L. Sturchio, Friends’ Board Chair and past chairman at Rabin Martin, a global health strategy consulting firm. “With increased funding, every $1 invested in the Global Fund will return $31. This is a smart investment that will save lives and enable the Global Fund to avert more than 450 million infections or cases. This is such an important opportunity, but we can’t get there without continued U.S. leadership.”

Learn more:

The Global Fund’s Seventh Replenishment Investment Case

Bipartisan Group of 137 Members of Congress Call for Increased U.S. Pledge to the Global Fund

Film: We Will Keep Fighting Until Our Last Breath


Friends of the Global Fight Against AIDS, Tuberculosis and Malaria advocates for U.S. support of the Global Fund, and the goal to end the epidemics of AIDS, tuberculosis and malaria. For more information about Friends of the Global Fight, visit


The Global Fund is a partnership designed to accelerate the end of AIDS, tuberculosis and malaria as epidemics. As an international organization, the Global Fund mobilizes and invests more than US$4 billion a year to support programs run by local experts in more than 120 countries. In partnership with governments, civil society, technical agencies, the private sector, faith-based organizations and people affected by the diseases, the Global Fund is challenging barriers and embracing innovation. Learn more at


Rachel Irwin
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